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Alternatives to OpenAI Agents SDK

OpenAI Agents SDK is an agent framework by OpenAI: Python SDK for multi-agent workflows with handoffs, guardrails, sessions and built-in tracing, usable with OpenAI and other LLMs. If it doesn't fit your setup, these 12 agent frameworks cover similar ground. They are ordered by how closely they match OpenAI Agents SDK and by our rank, which weighs adoption, freshness and documentation; money never changes the order. PraisonAI leads the list (supports JavaScript). Each entry shows data reasons to switch, and you can open a side-by-side comparison with OpenAI Agents SDK.

Updated Oct 26, 2026 · Built from catalog data; how we rank and grade

You're replacing

OpenAI Agents SDK

Python SDK for multi-agent workflows with handoffs, guardrails, sessions and built-in tracing, usable with OpenAI and other LLMs.

12 alternatives

Ordered by how closely each matches OpenAI Agents SDK (shared product, category or stated alternative) and by rank.

  1. 1
    PraisonAI

    Mervin Praison

    Python framework for multi-agent teams and workflows, with a CLI and Docker, MCP and A2A deployment options.

    • Supports JavaScript

    ★ 9.3K↓ 4.6K/wkLast active Oct 24, 2026Compare →

  2. 2
    Pipecat

    Daily

    Open-source Python framework for real-time voice and multimodal agents, built from composable pipelines with handoffs between specialist agents.

    • 16.8K GitHub stars
    • Active in the last 30 days

    ★ 16.8K↓ 373.6K/wkLast active Oct 24, 2026Compare →

  3. 3
    AgentScope

    Alibaba Tongyi Lab

    Python agent framework from Alibaba that lets the model drive tool use, with team pipelines, MCP, agent skills, A2A, memory and tracing.

    • 33.8K GitHub stars
    • Active in the last 30 days

    ★ 33.8K↓ 50.9K/wkLast active Oct 23, 2026Compare →

  4. 4
    Microsoft Agent Framework

    Microsoft

    Open framework for building and hosting production-grade AI agents and multi-agent workflows in .NET and Python.

    • Supports C# and Go

    ★ 14.3K↓ 47.6K/wkLast active Oct 24, 2026Compare →

  5. 5
    OpenAI Swarm

    OpenAI

    Experimental Python library that teaches agent handoffs on the Chat Completions API; OpenAI now points users to its Agents SDK.

    • 22.1K GitHub stars
    • Open source (MIT)

    ★ 22.1KLast active Apr 15, 2026

  6. 6
    Strands Agents

    AWS

    Open-source Python and TypeScript SDK for model-driven agents, with tools, MCP, multi-agent patterns and streaming.

    • Supports TypeScript

    ★ 8.9K↓ 8.9M/wkLast active Oct 24, 2026

  7. 7
    GitHub Copilot SDK

    GitHub

    Multi-language SDKs for embedding the GitHub Copilot agent runtime, with planning, tool calls and file edits, in your apps.

    • Supports TypeScript and Go

    ★ 10.6K↓ 1.2M/wkLast active Oct 24, 2026

  8. 8
    LlamaIndex

    LlamaIndex

    Open-source Python toolkit for RAG and agents over your own data, with event-driven workflows and 300+ integration packages.

    • 52.6K GitHub stars
    • Active in the last 30 days

    ★ 52.6K↓ 1.4M/wkLast active Oct 14, 2026

  9. 9
    Claude Agent SDK (Python)

    Anthropic

    Python SDK that runs the Claude Code agent loop inside your own program, with custom tools and hooks written as Python functions.

    • 8.3K GitHub stars
    • Active in the last 30 days

    ★ 8.3K↓ 7.9M/wkLast active Oct 24, 2026

  10. 10
    Genkit

    Google

    Open-source Firebase framework for AI features and agent workflows in JavaScript, Go, Python and Dart, with model plugins.

    • Supports TypeScript and JavaScript

    ★ 6.5K↓ 95.8K/wkLast active Oct 23, 2026

  11. 11
    Pi Agent Core

    Earendil

    Minimal TypeScript agent harness with an agent runtime, multi-provider LLM API, terminal UI and coding agent CLI that users extend themselves.

    • More GitHub stars (117.6K)
    • Supports TypeScript

    ★ 117.6K↓ 5.1M/wkLast active Oct 24, 2026

  12. 12
    Coinbase AgentKit

    Coinbase

    Coinbase toolkit that gives AI agents a crypto wallet and onchain actions, framework- and wallet-agnostic.

    • Supports JavaScript

    ★ 1.3K↓ 1.8K/wkLast active Oct 14, 2026

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