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Alternatives to AgentScope

AgentScope is an agent framework by Alibaba Tongyi Lab: Python agent framework from Alibaba that lets the model drive tool use, with team pipelines, MCP, agent skills, A2A, memory and tracing. If it doesn't fit your setup, these 12 agent frameworks cover similar ground. They are ordered by how closely they match AgentScope and by our rank, which weighs adoption, freshness and documentation; money never changes the order. PraisonAI leads the list (supports JavaScript). Each entry shows data reasons to switch, and you can open a side-by-side comparison with AgentScope.

Updated Oct 26, 2026 · Built from catalog data; how we rank and grade

You're replacing

AgentScope

Python agent framework from Alibaba that lets the model drive tool use, with team pipelines, MCP, agent skills, A2A, memory and tracing.

12 alternatives

Ordered by how closely each matches AgentScope (shared product, category or stated alternative) and by rank.

  1. 1
    PraisonAI

    Mervin Praison

    Python framework for multi-agent teams and workflows, with a CLI and Docker, MCP and A2A deployment options.

    • Supports JavaScript

    ★ 9.3K↓ 4.6K/wkLast active Oct 24, 2026Compare →

  2. 2
    Pipecat

    Daily

    Open-source Python framework for real-time voice and multimodal agents, built from composable pipelines with handoffs between specialist agents.

    • 16.8K GitHub stars
    • Active in the last 30 days

    ★ 16.8K↓ 373.6K/wkLast active Oct 24, 2026Compare →

  3. 3

    Python SDK for multi-agent workflows with handoffs, guardrails, sessions and built-in tracing, usable with OpenAI and other LLMs.

    • 30.3K GitHub stars
    • Active in the last 30 days

    ★ 30.3K↓ 4.5M/wkLast active Oct 22, 2026Compare →

  4. 4

    Open framework for building and hosting production-grade AI agents and multi-agent workflows in .NET and Python.

    • Supports C# and Go

    ★ 14.3K↓ 47.6K/wkLast active Oct 24, 2026Compare →

  5. 5

    Experimental Python library that teaches agent handoffs on the Chat Completions API; OpenAI now points users to its Agents SDK.

    • 22.1K GitHub stars
    • Open source (MIT)

    ★ 22.1KLast active Apr 15, 2026

  6. 6
    LlamaIndex

    LlamaIndex

    Open-source Python toolkit for RAG and agents over your own data, with event-driven workflows and 300+ integration packages.

    • 52.6K GitHub stars
    • Active in the last 30 days

    ★ 52.6K↓ 1.4M/wkLast active Oct 14, 2026

  7. 7
    LangChain

    LangChain

    Python framework of interoperable components and integrations for building agents and LLM apps, with LangGraph and Deep Agents layered above it.

    • More GitHub stars (148.4K)

    ★ 148.4K↓ 37.3M/wkLast active Oct 24, 2026

  8. 8
    LangGraph

    LangChain

    Low-level Python orchestration framework for long-running stateful agents, with durable execution, human review points and short- and long-term memory.

    • 43.8K GitHub stars
    • Active in the last 30 days

    ★ 43.8K↓ 13.1M/wkLast active Oct 24, 2026

  9. 9
    Pydantic AI

    Pydantic

    Typed Python SDK for building agents with swappable model providers, plus optional capabilities for memory, sub-agents, planning and durable execution.

    • 20.8K GitHub stars
    • Active in the last 30 days

    ★ 20.8K↓ 1.5M/wkLast active Oct 24, 2026

  10. 10

    Open-source toolkit for building, evaluating and deploying agents in Python, TypeScript, Go, Java and Kotlin, tuned for Gemini but model-agnostic.

    • Supports TypeScript and Go

    ★ 22K↓ 2.4M/wkLast active Oct 24, 2026

  11. 11
    Agno

    Agno

    Python framework and runtime for building agents, serving them over a REST API and MCP server, and managing them from a web control plane.

    • 42.9K GitHub stars
    • Active in the last 30 days

    ★ 42.9K↓ 519.4K/wkLast active Oct 24, 2026

  12. 12
    Genkit

    Google

    Open-source Firebase framework for AI features and agent workflows in JavaScript, Go, Python and Dart, with model plugins.

    • Supports TypeScript and JavaScript

    ★ 6.5K↓ 95.8K/wkLast active Oct 23, 2026