Atomic Agents vs Microsoft Agent Framework

Atomic Agents and Microsoft Agent Framework are both agent frameworks for Python. Atomic Agents is published by Eigenwise and Microsoft Agent Framework by Microsoft. On GitHub, Microsoft Agent Framework has 14,302 stars and Atomic Agents has 6,304. Both were last active in Oct 2026. The table lines up where they differ (publisher, GitHub stars, weekly downloads and languages) and has the install commands for both. Everything here comes from the listings' public sources and is refreshed daily. Atomic Agents describes itself as: Lightweight Python framework for composing AI agents and tools as small, typed pieces built on Instructor and Pydantic. Microsoft Agent Framework: Open framework for building and hosting production-grade AI agents and multi-agent workflows in .NET and Python. Licenses: Atomic Agents MIT, Microsoft Agent Framework MIT.