Ax vs Microsoft Agent Framework

Ax and Microsoft Agent Framework are both agent frameworks for Python. Ax is published by Ax and Microsoft Agent Framework by Microsoft. On GitHub, Microsoft Agent Framework has 14,302 stars and Ax has 2,969. Both were last active in Oct 2026. The table lines up where they differ (publisher, license, GitHub stars and weekly downloads) and has the install commands for both. Everything here comes from the listings' public sources and is refreshed daily. Ax describes itself as: DSPy-style toolkit for typed LLM signatures, agents and flows, TypeScript-first with Python, Java, C++, Go and Rust libraries. Microsoft Agent Framework: Open framework for building and hosting production-grade AI agents and multi-agent workflows in .NET and Python. Licenses: Ax Apache-2.0, Microsoft Agent Framework MIT.