Alternatives to Agno
Agno is an agent framework by Agno: Python framework and runtime for building agents, serving them over a REST API and MCP server, and managing them from a web control plane. If it doesn't fit your setup, these 12 agent frameworks cover similar ground. They are ordered by how closely they match Agno and by our rank, which weighs adoption, freshness and documentation; money never changes the order. LlamaIndex leads the list (52.6K GitHub stars; active in the last 30 days). Each entry shows data reasons to switch, and you can open a side-by-side comparison with Agno.
Updated Oct 26, 2026 · Built from catalog data; how we rank and grade
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Agno
Python framework and runtime for building agents, serving them over a REST API and MCP server, and managing them from a web control plane.
12 alternatives
Ordered by how closely each matches Agno (shared product, category or stated alternative) and by rank.
- 1LlamaIndex
LlamaIndex
Open-source Python toolkit for RAG and agents over your own data, with event-driven workflows and 300+ integration packages.
- 52.6K GitHub stars
- Active in the last 30 days
★ 52.6K↓ 1.4M/wkLast active Oct 14, 2026Compare →
AFreshness: A–Security: not graded yet - 2LangChain
LangChain
Python framework of interoperable components and integrations for building agents and LLM apps, with LangGraph and Deep Agents layered above it.
- More GitHub stars (148.4K)
★ 148.4K↓ 37.3M/wkLast active Oct 24, 2026Compare →
AFreshness: A–Security: not graded yet - 3LangGraph
LangChain
Low-level Python orchestration framework for long-running stateful agents, with durable execution, human review points and short- and long-term memory.
- 43.8K GitHub stars
- Active in the last 30 days
★ 43.8K↓ 13.1M/wkLast active Oct 24, 2026Compare →
AFreshness: A–Security: not graded yet - 4CrewAI
CrewAI
Open-source Python framework for multi-agent workflows, with role-based Crews and event-driven Flows.
- 60.1K GitHub stars
- Active in the last 30 days
★ 60.1K↓ 644.6K/wkLast active Oct 24, 2026Compare →
AFreshness: A–Security: not graded yet - 5CAMEL
CAMEL-AI
Open-source Python framework for multi-agent systems: agent societies, memory, RAG, code interpreters, synthetic data and large-scale simulation.
- 18K GitHub stars
- Active in the last 30 days
★ 18K↓ 20.1K/wkLast active Oct 19, 2026
AFreshness: A–Security: not graded yet - 6AutoGen
Microsoft
Archived Microsoft Python framework for multi-agent apps; Microsoft directs new users to Microsoft Agent Framework.
- 61.5K GitHub stars
- Active in the last 30 days
★ 61.5K↓ 89K/wkLast active Oct 16, 2026Compare →
AFreshness: A–Security: not graded yet - 7activegraph
yoheinakajima
Event-sourced Python graph runtime where agent behaviors react to a shared graph, with an audit trail and fork-and-diff replay.
- Active in the last 30 days
- Open source (Apache-2.0)
★ 707↓ 603/wkLast active Sep 26, 2026
AFreshness: A–Security: not graded yet - 8MetaGPT
FoundationAgents
Python multi-agent framework that gives LLM agents software-company roles and SOPs to turn a one-line requirement into a project repository.
- 71K GitHub stars
- Open source (MIT)
★ 71K↓ 622/wkLast active Jan 21, 2026
DFreshness: D–Security: not graded yet - 9Youtu-Agent
Tencent
Framework for building, running and evaluating autonomous agents, with a planner-based multi-agent mode, skills and agent RL training.
- 4.6K GitHub stars
- For Python
★ 4.6K↓ 23/wkLast active Mar 21, 2026
DFreshness: D–Security: not graded yet - 10Pydantic AI
Pydantic
Typed Python SDK for building agents with swappable model providers, plus optional capabilities for memory, sub-agents, planning and durable execution.
- 20.8K GitHub stars
- Active in the last 30 days
★ 20.8K↓ 1.5M/wkLast active Oct 24, 2026
AFreshness: A–Security: not graded yet - 11
Open-source toolkit for building, evaluating and deploying agents in Python, TypeScript, Go, Java and Kotlin, tuned for Gemini but model-agnostic.
- Supports TypeScript and Go
★ 22K↓ 2.4M/wkLast active Oct 24, 2026
AFreshness: A–Security: not graded yet - 12Genkit
Google
Open-source Firebase framework for AI features and agent workflows in JavaScript, Go, Python and Dart, with model plugins.
- Supports TypeScript and JavaScript
★ 6.5K↓ 95.8K/wkLast active Oct 23, 2026
AFreshness: A–Security: not graded yet
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- ComparisonAgno vs LlamaIndex
- ComparisonAgno vs LangChain
- ComparisonAgno vs CrewAI
- ComparisonAgno vs LangGraph
- ComparisonAgno vs AutoGen
- Best ofBest agent frameworks for building AI agents
- AlternativesAlternatives to LlamaIndex
- AlternativesAlternatives to LangChain
- AlternativesAlternatives to LangGraph
- AlternativesAlternatives to CrewAI
- AlternativesAlternatives to CAMEL