AutoGen vs LangChain

AutoGen and LangChain are both agent frameworks for Python. AutoGen is published by Microsoft and LangChain by LangChain. On GitHub, LangChain has 148,371 stars and AutoGen has 61,549. Both were last active in Oct 2026. The table lines up where they differ (publisher, license and weekly downloads) and has the install commands for both. Everything here comes from the listings' public sources and is refreshed daily. AutoGen describes itself as: Archived Microsoft Python framework for multi-agent apps; Microsoft directs new users to Microsoft Agent Framework. LangChain: Python framework of interoperable components and integrations for building agents and LLM apps, with LangGraph and Deep Agents layered above it. Licenses: AutoGen CC-BY-4.0, LangChain MIT.