Amazon Bedrock AgentCore SDK vs AutoGen
Amazon Bedrock AgentCore SDK and AutoGen are both agent frameworks for Python. Amazon Bedrock AgentCore SDK is published by AWS and AutoGen by Microsoft. On GitHub, AutoGen has 61,549 stars and Amazon Bedrock AgentCore SDK has 780. Both were last active in Oct 2026. The table lines up where they differ (publisher, license, GitHub stars and weekly downloads) and has the install commands for both. Everything here comes from the listings' public sources and is refreshed daily. Amazon Bedrock AgentCore SDK describes itself as: Python SDK for deploying agents to Amazon Bedrock AgentCore, a managed runtime with memory, gateway, tools and observability. AutoGen: Archived Microsoft Python framework for multi-agent apps; Microsoft directs new users to Microsoft Agent Framework. Licenses: Amazon Bedrock AgentCore SDK Apache-2.0, AutoGen CC-BY-4.0.
Updated Oct 26, 2026 · Built from catalog data; how we rank and grade
Amazon Bedrock AgentCore SDK
AWS
Python SDK for deploying agents to Amazon Bedrock AgentCore, a managed runtime with memory, gateway, tools and observability.
AutoGen
Microsoft
Archived Microsoft Python framework for multi-agent apps; Microsoft directs new users to Microsoft Agent Framework.
Who should pick which
- Pick Amazon Bedrock AgentCore SDK if you want MCP support built in.
- Pick Amazon Bedrock AgentCore SDK if you want a stable release (AutoGen is marked experimental).
- Pick AutoGen if you need several agents working together.
- AutoGen has the larger community: 61,549 GitHub stars against 780.
From listing data only. We don't pick a winner on security beyond the grades; read how grades work.
Side by side
| Fact | Amazon Bedrock AgentCore SDK | AutoGen |
|---|---|---|
| Type | Harness | Harness |
| Publisher | AWS | Microsoft |
| License | Apache-2.0 | CC-BY-4.0 |
| Pricing | Not stated | Not stated |
| Runs | Not stated | Not stated |
| Auth | Not stated | Not stated |
| Hosts supported | Not stated | Not stated |
| Tools | Not listed yet | Not listed yet |
| Security grade | –Security: not graded yet | –Security: not graded yet |
| Freshness grade | AFreshness: A | AFreshness: A |
| GitHub stars | 780 | 61,549 |
| Weekly downloads | 1,598,976 | 88,975 |
| Last release | Oct 23, 2026 | Sep 30, 2025 |
| Last activity | Oct 23, 2026 | Oct 16, 2026 |
Facts from each listing's public sources, checked daily. Tool lists arrive with tool scans.
Install
Amazon Bedrock AgentCore SDK
pip install bedrock-agentcore
AutoGen
pip install autogen-agentchat
Also consider
- 0.853score
LlamaIndex
LlamaIndex
Open-source Python toolkit for RAG and agents over your own data, with event-driven workflows and 300+ integration packages.
HarnessAFreshness: A★ 52.6K↓ 1.4M/wk - 0.753score
LangChain
LangChain
Python framework of interoperable components and integrations for building agents and LLM apps, with LangGraph and Deep Agents layered above it.
HarnessAFreshness: A★ 148.4K↓ 37.3M/wk - 0.748score
LangGraph
LangChain
Low-level Python orchestration framework for long-running stateful agents, with durable execution, human review points and short- and long-term memory.
HarnessAFreshness: A★ 43.8K↓ 13.1M/wk
Questions
- Is Amazon Bedrock AgentCore SDK or AutoGen more popular?
- AutoGen has more GitHub stars (61,549 against 780). Stars measure attention, not quality, so check freshness and docs too.
- Are Amazon Bedrock AgentCore SDK and AutoGen open source?
- Yes: Amazon Bedrock AgentCore SDK is Apache-2.0 and AutoGen is CC-BY-4.0.
Related
- AlternativesAlternatives to Amazon Bedrock AgentCore SDK
- ComparisonAmazon Bedrock AgentCore SDK vs LangChain
- ComparisonAmazon Bedrock AgentCore SDK vs CrewAI
- ComparisonAmazon Bedrock AgentCore SDK vs LlamaIndex
- ComparisonAutoGen vs LlamaIndex
- ComparisonAutoGen vs Strands Agents
- ComparisonAutoGen vs GitHub Copilot SDK
Cite this page
Amazon Bedrock AgentCore SDK vs AutoGen. Agent Mart. https://agentmart.dev/compare/amazon-bedrock-agentcore-sdk-vs-autogen (last updated 2026-10-26)