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Best agent skills for science and biology

We found 489 agent skills for science and biology in the catalog; these are the 15 that rank highest. The order comes from our rank, which weighs adoption, freshness, documentation and publisher identity. Nobody can pay for a place on this list. complexa-target, rfd4-proteina-nim and polars-bio lead it. complexa-target comes from the largest repository here (3,718 stars). 10 of the 15 had activity in the last 30 days. Each entry lists why it made the list and links to its install page.

Updated Oct 26, 2026 · Built from catalog data; how we rank and grade

Top 15 of 489

  1. 1
    complexa-target

    Ohad Mosafi <omosafi@nvidia.com>

    Add, edit, inspect, or validate Proteina-Complexa target definitions for protein binders, ligand binders, and AME motif scaffolding.

    • Largest repository here (3,718 stars)
    • Active in the last 30 days
    • Open source (Apache-2.0)

    ★ 3.7KLast active Oct 21, 2026Claude Code, Claude apps, Codex, Cursor +6

  2. 2
    rfd4-proteina-nim

    NVIDIA BioNeMo <bionemofeedback@nvidia.com>

    Run RFD4-Proteina NIM for joint protein structure and sequence design, conditioned generation, and reward-guided search using the NVIDIA hosted API or a…

    • Largest repository here (3,718 stars)
    • Active in the last 30 days
    • Open source (Apache-2.0)

    ★ 3.7KLast active Oct 21, 2026Claude Code

  3. 3
    polars-bio

    ClawBio (adapted from K-Dense scientific-agent-skills/polars-bio)

    Fast genomic interval operations (overlap, nearest, merge, coverage, cluster, complement, subtract, count-overlaps), multi-format bioinformatics I/O…

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (Apache-2.0)

    ★ 1.2KLast active Sep 25, 2026Claude Code, Claude apps, Codex, Cursor +6

  4. 4
    ukb-ppp-region-fetch

    ClawBio

    Fetch a regional slice of plasma pQTL summary statistics from the UK Biobank Pharma Proteomics Project (UKB-PPP; Sun 2023 Nature) for a specific (protein…

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 22, 2026Claude Code, Claude apps, Codex, Cursor +6

  5. 5
    arrayexpress-fetch

    Nikolai Hecker, UK Dementia Research Institute

    Query metadata and download data from ArrayExpress, EMBL-EBI's functional genomics collection, now hosted inside BioStudies.

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 2, 2026Claude Code, Claude apps, Codex, Cursor +6

  6. 6
    struct-predictor

    ClawBio

    Protein structure prediction with Boltz-2 (default) or OpenFold3.

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 5, 2026Claude Code, Claude apps, Codex, Cursor +6

  7. 7
    rare-high-impact-variants

    Manuel Corpas

    Count rare, high-impact loss-of-function variants carried in a VCF, annotated with molecular consequence and population allele frequency

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 19, 2026Claude Code, Claude apps, Codex, Cursor +6

  8. 8
    organ-aging-studio

    ClawBio hackathon contributor

    Interactive Goeminne proteomic aging clock with organ filters and per-protein contribution breakdown (protein NPX × coefficient).

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 19, 2026Claude Code, Claude apps, Codex, Cursor +6

  9. 9
    lit-synthesizer

    Sooraj (github.com/sooraj-codes)

    Search PubMed and bioRxiv for bioinformatics literature, synthesise results into a structured report, and build a citation graph — all locally, with a…

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 20, 2026Claude Code, Claude apps, Codex, Cursor +6

  10. 10
    celltype-specificity-profiler

    Jacky Siu

    Given a gene and a single-cell atlas, compute how cell-type-specific its expression is — the tau specificity index, Sarle's expression bimodality coefficient…

    • Repository has 1.2K stars
    • Active in the last 30 days
    • Open source (MIT)

    ★ 1.2KLast active Oct 19, 2026Claude Code, Claude apps, Codex, Cursor +6

  11. 11
    nvmolkit-usage

    Kevin Boyd (@scal444)

    Use when writing or debugging nvMolKit Python code for GPU-accelerated RDKit fingerprints, similarity, conformers, clustering, and molecular searches.

    • Largest repository here (3,718 stars)
    • Open source (Apache-2.0)

    ★ 3.7KLast active Sep 23, 2026Claude Code, Claude apps, Codex, Cursor +6

  12. 12
    xena-tcga-gene-query

    lishensuo

    Query TCGA tumor biology through the ucscxenatoolspy API.

    • Repository has 1.2K stars
    • Open source (MIT)
    • Ships helper scripts

    ★ 1.2KLast active Sep 11, 2026Claude Code, Claude apps, Codex, Cursor +6

  13. 13
    scrna-orchestrator

    Yonghao Zhao

    Local Scanpy pipeline for single-cell RNA-seq QC, optional doublet detection, clustering, marker discovery, optional CellTypist annotation, optional latent…

    • Repository has 1.2K stars
    • Open source (MIT)
    • Ships helper scripts

    ★ 1.2KLast active Sep 11, 2026Claude Code, Claude apps, Codex, Cursor +6

  14. 14
    analyze-fasta

    Santiago Rodriguez Salinas

    Analyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython…

    • Repository has 1.2K stars
    • Open source (MIT)
    • Ships helper scripts

    ★ 1.2KLast active Sep 17, 2026Claude Code, Claude apps, Codex, Cursor +6

  15. 15
    busco-assessor

    ClawBio Contributors

    Genome, transcriptome, and protein completeness assessment via BUSCO v6.

    • Repository has 1.2K stars
    • Open source (MIT)
    • Ships helper scripts

    ★ 1.2KLast active Sep 11, 2026Claude Code, Claude apps, Codex, Cursor +6

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