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Alternatives to AG2

AG2 is an agent framework by AG2: Open-source Python framework for AI agents that cooperate on tasks, with human-in-the-loop workflows and multi-agent patterns. If it doesn't fit your setup, these 12 agent frameworks cover similar ground. They are ordered by how closely they match AG2 and by our rank, which weighs adoption, freshness and documentation; money never changes the order. Agent Squad leads the list (supports TypeScript and Swift). Each entry shows data reasons to switch, and you can open a side-by-side comparison with AG2.

Updated Oct 26, 2026 · Built from catalog data; how we rank and grade

You're replacing

AG2

Open-source Python framework for AI agents that cooperate on tasks, with human-in-the-loop workflows and multi-agent patterns.

12 alternatives

Ordered by how closely each matches AG2 (shared product, category or stated alternative) and by rank.

  1. 1
    Agent Squad

    2FastLabs

    Open-source framework that routes each user query to one of several AI agents, with Python, TypeScript and Swift runtimes.

    • Supports TypeScript and Swift

    ★ 7.8K↓ 1.5K/wkLast active Oct 2, 2026Compare →

  2. 2
    Pipecat

    Daily

    Open-source Python framework for real-time voice and multimodal agents, built from composable pipelines with handoffs between specialist agents.

    • More GitHub stars (16.8K)

    ★ 16.8K↓ 373.6K/wkLast active Oct 24, 2026Compare →

  3. 3
    OGX (formerly Llama Stack)

    OGX

    OpenAI-compatible agentic API server for inference, vector stores, files and skills, on any model or infrastructure.

    • 8.4K GitHub stars
    • Active in the last 30 days

    ★ 8.4K↓ 14.2K/wkLast active Oct 24, 2026Compare →

  4. 4
    txtai

    NeuML

    All-in-one Python AI framework for embeddings-based semantic search, LLM pipelines, workflows and agents.

    • More GitHub stars (13K)

    ★ 13K↓ 3.3K/wkLast active Oct 22, 2026Compare →

  5. 5
    Microsoft Agent Framework

    Microsoft

    Open framework for building and hosting production-grade AI agents and multi-agent workflows in .NET and Python.

    • More GitHub stars (14.3K)
    • Supports C# and Go

    ★ 14.3K↓ 47.6K/wkLast active Oct 24, 2026Compare →

  6. 6
    LlamaIndex

    LlamaIndex

    Open-source Python toolkit for RAG and agents over your own data, with event-driven workflows and 300+ integration packages.

    • More GitHub stars (52.6K)

    ★ 52.6K↓ 1.4M/wkLast active Oct 14, 2026

  7. 7
    Genkit

    Google

    Open-source Firebase framework for AI features and agent workflows in JavaScript, Go, Python and Dart, with model plugins.

    • Supports TypeScript and JavaScript

    ★ 6.5K↓ 95.8K/wkLast active Oct 23, 2026

  8. 8
    Strands Agents

    AWS

    Open-source Python and TypeScript SDK for model-driven agents, with tools, MCP, multi-agent patterns and streaming.

    • Supports TypeScript

    ★ 8.9K↓ 8.9M/wkLast active Oct 24, 2026

  9. 9
    Ax

    Ax

    DSPy-style toolkit for typed LLM signatures, agents and flows, TypeScript-first with Python, Java, C++, Go and Rust libraries.

    • Supports TypeScript and Java

    ★ 3K↓ 27.2K/wkLast active Oct 21, 2026

  10. 10
    GitHub Copilot SDK

    GitHub

    Multi-language SDKs for embedding the GitHub Copilot agent runtime, with planning, tool calls and file edits, in your apps.

    • More GitHub stars (10.6K)
    • Supports TypeScript and Go

    ★ 10.6K↓ 1.2M/wkLast active Oct 24, 2026

  11. 11
    LangChain

    LangChain

    Python framework of interoperable components and integrations for building agents and LLM apps, with LangGraph and Deep Agents layered above it.

    • More GitHub stars (148.4K)

    ★ 148.4K↓ 37.3M/wkLast active Oct 24, 2026

  12. 12
    PraisonAI

    Mervin Praison

    Python framework for multi-agent teams and workflows, with a CLI and Docker, MCP and A2A deployment options.

    • Supports JavaScript

    ★ 9.3K↓ 4.6K/wkLast active Oct 24, 2026

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